Horizon Labradors

AKC Registered
Labrador Retriever Puppies
Chocolate, Yellow & Black

 

It is very sad that alot of breeders don't have a clue what they are breeding together, you can be assured Horizon Labradors is committed to providing you with not only a puppy that will grow up to be a beautiful dog but a dog that has excellent quality backed up with proven genetics.
If you don't decide to get your new puppy from Horizon Labradors, please look for a responsible breeder that is improving the breed & breeding good quality dogs backed up with genetic testing!!
WE KNOW 100% THAT WE WILL NEVER PRODUCE PUPPIES THAT WILL BE AFFECTED BY EIC, CNM, DM, PRA/PRCD OR RD/OSD, because all our dogs are tested before they are bred and bred accordingly.

 

Below is a list of the Genetic testing that we are getting done on our breeding dogs.

OFA testing

Hip dysplasia is an abnormal formation of the hip socket that, in its more severe form, can eventually cause crippling lameness and painful arthritis of the joints. It is a polygenic trait, that is affected by environmental factors in the production of the final phenotype.
Elbow dysplasia is a condition involving multiple developmental abnormalities of the elbow-joint in the dog, specifically the growth of cartilage or the structures surrounding it.

OFA grades hips with Excellent, Good or Fair.  Elbows get a score of Normal (Good).

 

Canine Exercise Induced Collapse (EIC) ~ Dogs clinically affected by Exercise Induced Collapse (EIC) will often begin to exhibit leg weakness followed by a complete collapse after just 5 to 15 minutes of strenuous activity. The severity and duration of these spells can vary depending on the environment.

There are 3 possible genotypes reported for Exercise Induced Collapse:

  1. CLEAR (those having 2 copies of the normal allele and appear to be normal).
  2. CARRIER (those having 1 copy of the normal allele and 1 copy of the mutation but appear to be normal). Note:  CARRIERS can be bred to CLEAR.
  3. AFFECTED (those having 2 copies of the mutation and will likely show clinical signs for EIC) Note:  AFFECTED should never be bred.
Please watch this video on YouTube, it only takes 1 min 16 sec to see the devastating effects of EIC EIC YouTube Video



 

Centronuclear Myopathy (CNM) is an inherited autosomal recessive disorder and is characterized by muscle weakness and exercise intolerance.

There are 3 possible genotypes reported for Centronuclear Myopathy:

  1. CLEAR (those having 2 copies of the normal allele and appear to be normal).
  2. CARRIER (those having 1 copy of the normal allele and 1 copy of the mutation but appear to be normal).
  3. AFFECTED (those having 2 copies of the mutation and will likely begin to show fatigue, muscle weakness and exercise intolerance after a few months of age.

 

Canine Degenerative Myelopathy (DM) is a devastating degenerative disease of the spinal cord that can progress rapidly and cause weakness in the hind limbs and eventually paraplegia among genotypically affected dogs.
There are 3 possible genotypes reported for Canine Degenerative Myopathy:
  1. CLEAR (those having 2 copies of the normal allele and appear to be normal).
  2. CARRIER (those having 1 copy of the normal allele and 1 copy of the mutation but appear to be normal).
  3. AT RISK (those having 2 copies of the mutation and will likely show clinical signs.)

CARDIAC exams test for congenital heart diseases in dogs.  They are malformations of the heart or great vessels.

PRA/PRCD

Progressive retinal Atrophy, progressive Rod-cone degeneration (PRA-prcd) is a late onset, inherited eye disease affecting Labrador Retrievers. PRA-prcd occurs as a result of degeneration of both rod and cone type Photoreceptor Cells of the Retina, which are important for vision in dim and bright light, respectively. Evidence of retinal disease in affected Labrador Retrievers can first be seen on an Electroretinogram around 1.5 years of age, but most affected dogs will not show signs of vision loss until 4 to 6 years of age or later. The rod type cells are affected first and affected dogs will initially have vision deficits in dim light (night blindness) and loss of peripheral vision. Over time affected dogs continue to lose night vision and begin to show visual deficits in bright light. Other signs of progressive retinal atrophy involve changes in reflectivity and appearance of a structure behind the retina called the Tapetum that can be observed on a veterinary eye exam. Although there is individual and breed variation in the age of onset and the rate of disease progression, the disease eventually progresses to complete blindness in most dogs. Other inherited disorders of the eye can appear similar to PRA-prcd. Genetic testing may help clarify if a dog is affected with PRA-prcd or another inherited condition of the eye.
There are 3 possible genotypes reported for PRA/PRCD:
  1. CLEAR (those having 2 copies of the normal allele and appear to be normal).
  2. CARRIER (those having 1 copy of the normal allele and 1 copy of the mutation but appear to be normal).
  3. AT RISK (those having 2 copies of the mutation and will likely show clinical signs.)

RD/OSD

Retinal dysplasia/oculoskeletal dysplasia 1 is an inherited Collagen disorder affecting Labrador retrievers. Dwarfism and eye abnormalities may be apparent as early as 4 to 6 weeks of age in affected puppies. The dwarfism is characterized by shortened forelimbs that become curved as the dog grows. In puppies, the top of the head may be noticeably dome shaped compared to littermates. A range of eye abnormalities is visible on a veterinary eye exam of which retinal detachment and cataracts are the most common. Carrier dogs do not have skeletal changes but may have mild eye abnormalities, including retinal folds.
There are 3 possible genotypes reported for RD/OSD:
  1. CLEAR (those having 2 copies of the normal allele and appear to be normal).
  2. CARRIER (those having 1 copy of the normal allele and 1 copy of the mutation but appear to be normal).
  3. AT RISK (those having 2 copies of the mutation and will likely show clinical signs.)